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What are rare cannabinoids?

The phrase “rare cannabinoids” can be a bit misleading because it sounds as if they are a new discovery when in fact, these compounds have been around for just as long as CBD itself. CBC, CBG, and CBN are considered to be “rare” or “minor” cannabinoids because the extraction and study of these fascinating compounds is fairly recent.

Because the science involved is cutting edge, there is considerable cost and effort put into the extraction process. Separating these cannabinoids from the hemp plant is difficult and expensive—but worth it. The effects of these compounds are multiplied when added to CBD.

Here at Designer Green, we use the highest quality CBD and add these rare cannabinoids in large ratios to create our tinctures. These rare cannabinoids affect the body differently than CBD alone would and we have added them to our formulas for their specific uses.


What is hemp-derived CBD?

Cannabidiol (CBD) is a compound that is extracted from the hemp plant and used to formulate a wide variety of products and tinctures. 

For thousands of years, industrial hemp plants were cultivated predominantly for their fiber and seeds. As a result of the passing of the 2018 Farm Bill, growing hemp has now become federally legalized across all 50 states. Today farmers are now cultivating hemp using strains with genetics that yield the highest quantities of potent cannabidiol and other desired cannabinoids with high terpene content. We are proud to support America's farmers by offering CBD that is 100% grown in the USA. 



Broad-Spectrum vs CBD Isolate 

Broad-spectrum CBD differs from CBD Isolate in the way that it contains all of the compounds in the hemp plant (minus the THC.) 

CBD isolate is pure cannabidiol extracted from the hemp plant.

Studies suggest these botanical cannabinoids are more effective when consumed together than when consumed on their own. The terpene molecules work in harmony with the cannabinoids for a stronger effect. This is what is known as the “Entourage Effect.” 

As research unfolds, you will likely hear more about using specific terpene profiles and certain cannabinoid compounds for more personal and targeted healing. The best part is, anyone can receive the benefits of these compounds without the presence of any THC.

What an exciting time to keep an eye on the research!


Rare Cannabinoids 

Cannabinoids engage with our endocannabinoid system, which is the chief regulatory network that is connected with other vital systems in our bodies. Each one will attach to the surface region of cells, where receptors are positioned. 

The effects of each cannabinoid depend upon the part of the brain they bind with. 

Let’s explore a few of these rare cannabinoids further. 



CBG stands for cannabigerol and is known as the “mother” cannabinoid because it is the fundamental cannabinoid from which all other cannabinoids are made from. CBG is only found in smaller quantities within the plant and therefore harder to obtain. 

Both of our premium tinctures Trifecta and The Day formulas contain CBG.

Links to research:

CBG has also demonstrated an ability to increase anandamide, commonly referred to as the “bliss molecule,” an endogenous cannabinoid that helps regulate a wide range of bodily functions, including appetite, sleep, mood, and the immune system. 

While research is still in the early states regarding all the rare cannabinoids, this particular study touches on the possibilities of using CBG to treat glaucoma. 

Check out this whitepaper on CBG for a deeper understanding of how it works with the body. 

Here is another link to a study about how CBG may help treat inflammatory bowel disease.



Cannabichromene or CBC is a powerful non-psychoactive cannabinoid that is extracted from the hemp plant. This particular compound does not necessarily get a lot of attention but has shown to have some profound benefits. Like CBG, CBC is only found in small quantities and therefore more difficult to obtain from the plant. 

Cannabichromene or “chrome” is found in both our daytime Trifecta formula and our nighttime Chrome formula.

Links to research:

One study, published in 2011 in the British Journal of Pharmacology, found that this cannabinoid blocks pain processing in the brain in a way that is very similar to opioids and THC. 

This study suggests it may be helpful for reducing inflammation. 

Take a look at this CBC whitepaper to learn more! 



CBN (cannabinol) is best known as the compound formed after THC ages. Because of this, it is usually found in high concentrations in older more mature plants. This mildly psychoactive compound is derived from tetrahydrocannabinolic acid (THC-A) after it is oxidized.

You can find CBN in our The Night Formula tincture. This premium product may intensify relaxation with powerful hemp-derived CBN. 

Links to research:

Check out this article to learn more about how CBN can help improve your sleep.

Studies on CBN also indicate that it also might be a potent antibacterial agent.

This rodent study also indicates that CBN might be effective in appetite stimulation. 

Click here to learn more about how CBN and other rare cannabinoids affect the body.